Proceedings: Osmolar relation between CSF and serum in hyperosmolar hypernatraemic dehydration.

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Osmolar relation between cerebrospinal fluid and serum in hyperosmolar hypernatraemic dehydration.

The relation between cerebrospinal fluid (CSF) and serum osmolality was studied in 16 patients with hyperosmolar hypernatraemic dehydration before treatment. After correcting shock and acidosis, 0-45% saline in 2-5 or 5% dextrose was infused in each patient over a 48- to 72-hour period. During rehydration, serum osmolality, electrolyte concentrations, urea nitrogen, and blood pH were measured s...

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Hypernatraemic dehydration in newborn infants

Hypernatraemic dehydration is a potentially lethal condition and is associated with cerebral oedema, intracranial haemorrhage, hydrocephalus and gangrene. The infant’s plasma sodium concentration is elevated due predominantly to loss of extracellular water. In the past, hypernatraemia occurred most frequently when artificial feeds of too high a sodium concentration were fed to babies. This was ...

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Dexamethasone in the treatment of hypernatraemic dehydration.

Ninety infants with severe hypernatraemic dehydration (plasma sodium greater than 150 mmol/l) were studied. Most had had a convulsion before admission. They were allocated to two treatment groups. Both groups received intravenous plasma followed by slow intravenous rehydration and correction of acidosis. In addition, one group received intramuscular phenobarbitone, the other group received dexa...

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Peripheral gangrene in hypernatraemic dehydration of infancy.

Gangrene of the extremities complicating diarrhoea and severe hypernatraemic dehydration occurred in 6 infants. This is a rare complication of gastroenteritis, and its association with hypernatraemia does not seem to have previously been emphasized. The increased blood viscosity resulting from serum hyperosmolarity may have been responsible for the gangrene, and studies in our patients suggeste...

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High calorie-osmolar feeding and hypertonic dehydration.

Taitz, L. S., and Byers, H. D. (1972). Archives of Disease in Childhood, 47, 257. High calorie/osmolar feeding and hypertonic dehydration. Analysis of the sodium content of milk taken from bottles brought by mothers to feed their babies while waiting in the postnatal clinic indicates that the tendency to use excessive amounts of milk powder in feeds is widespread. The effects of high solute/cal...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1975

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.50.4.331-b